The significant advantages are:
- After transfection and selection resulting cells show a better long term stability of expression
- Better yield of stable expressing cells
- Higher middle expression level of resistant cells. Consequently it is possible to isolate more cell clones with high expression level
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Our proprietary IGAMI technology uses special stabilizing and enhancing sequences.
These sequences integrate together with the transgene into the host chromatin and
prevent gene silencing of the neighbouring transgene. The resulting cell lines show
an increased recombinant protein expression and a better
long term expression stability
Using our IGAMI technology a fast and easy stable cell line
generation is possible.
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